In continuous efforts over years, PegBio Co. has developed proprietary methods of synthesis of mPEGs and their derivatives. mPEGs manufactured vary in molecular weight (2-50 kDa) and structures. In addition to production of linear and branched multi-armed PEGs current available on the market, the Company has also developed a new method to produce proprietary multiple branched PEGs (patents: ZL 02101672.0 and US 7,144,978 B2). The Company’s PEGs manufactured are characterized at high quality such as precise molecular weight (difference from target molecular weight < 10%), lower polydispersivity (PDI < 1.05) and less diol content (< 3%), low costs, and high production capacity (>200 kg/year). Moreover, the Company has effective and well-fined organic chemistry methods to produce a series of PEG derivatives such as mPEG-SC, mPEG-SS, mPEG-Mal and mPEG-Aldehyde, as activation groups for further PEGylation. The activation rate for these PEG derivatives are usually more than 80%.
The following are figures of PEGs analyses derived from PegBio Co.’s products and other company’s products.